Biostatistics Homework Help
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Probability in Health and Medicine
 Medical uncertainties and probability
 Elementary laws of probability
 Bayes’ Rule
 Sensitivityspecificity of a medical test
 Positive and negative predictive value
 Effect of prevalence
Confidence Intervals
 Sampling distributions and SEs
 Large sample CI for onesample mean and proportion
 Exact CI for proportion and median
 Large sample CI for differences between means and proportions
 Sample size for estimation
Statistical vs. Medical Significance
 Pvalue and level of significance
 The concept of statistical power
 Medical vs. statistical significance
 Sample size for significance and power analysis
 Chisquare test for simple situations
Some Statistical Tests for Quantitative Data
 Student’s ttest for onesample and twosample situations
 ANOVA for oneway and twoway tables
 Tukey test and Bonferroni procedures for multiple comparisons
 Test for medically significant gain and equivalence tes

Introduction to Designs for Clinical Trials
 Control group
 Randomization and matching
 Blinding and masking
 Oneway, twoway and repeated measures designs
 Crossover design
ROC Curves
 Review of sensitivityspecificity
 Serial and parallel tests
 ROC curve
 Predictivitybased ROC curve
 Clinical gains from a test
Relative Risk (RR) and Odds Ratio (OR)
 Definitions and applicability of RR and OR
 CI and test of hypothesis for RR
 CI and test of hypothesis for attributable risk
 CI and test of hypothesis for OR
Introductory Survival Analysis
 Censored durations and need of special methods
 Life table method
 KaplanMeier meth

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